Vardenafil for ED: Phase III Trial
International Journal of Impotence Research (2003)
Significantly improved IIEF scores vs placebo across all severity groups with rapid onset.
Vardenafil
Troche (50mg)Available in all 50 statesMarketing purposes only. Actual medications, if prescribed, are dispensed by a licensed pharmacy.
sexual health
VardenafilVardenafil
PDE5 inhibitor with the highest PDE5 selectivity and potency among the class. Duration 4 to 5 hours. Often used in combination troches for enhanced sexual function protocols.
Highest PDE5 selectivity
Rapid onset
Potent at lower doses
No commitment · HSA/FSA eligibleNo commitment · HSA/FSA eligible
How it works
Mechanism of action
Highly selective PDE5 inhibition with 10x greater potency than sildenafil at the PDE5 enzyme. Enhances NO/cGMP-mediated vasodilation in erectile tissue.
The baseline panel.
Every Marek client receives this baseline panel before a provider review. Your provider may add additional biomarkers based on your health history, symptoms, and goals, pulling from 1,000+ available markers. See more biomarkers →
Hormone Profile
12 markers
Sex hormones
- Total TestosteroneLC/MS
- Free TestosteroneEquilibrium Dialysis
- Estradiol, Sensitive / UltrasensitiveLC/MS
- Sex Hormone Binding Globulin (SHBG)
- ProgesteroneLC/MSFemale panel
- Prolactin
- Luteinizing Hormone (LH)
- Follicle-Stimulating Hormone (FSH)
- hCG, Total, QuantitativeFemale panel, pre-menopause
Adrenals & neurosteroids
- Cortisol
- DHEA-S
Growth hormone / IGF-1
- Insulin-Like Growth Factor I (IGF-1)
Thyroid Status
3 markers
Thyroid hormones
- Thyroid Stimulating Hormone (TSH)
- Free T4
- Free T3
Heart Health
9 markers
Cardiovascular health
- Total Cholesterol
- HDL Cholesterol
- LDL Cholesterol
- LDL:HDL Ratio
- VLDL Cholesterol
- Triglycerides
- Apolipoprotein-B (ApoB)
- C-Reactive Protein, High Sensitivity (hsCRP)
- Lipoprotein(a) (Lp(a))
Metabolism
3 markers
Insulin sensitivity
- Blood Glucose
- Fasting Insulin
- HbA1c
Organ Function
26 markers
Liver & pancreas
- AST
- ALT
- Bilirubin, Total
- γ-Glutamyl Transferase (GGT)
Kidney function
- BUN
- Creatinine w/ eGFR
Comprehensive Metabolic Panel (CMP)
- Glucose
- Blood Urea Nitrogen (BUN)
- Creatinine
- eGFR
- BUN/Creatinine Ratio
- Sodium
- Potassium
- Chloride
- Carbon Dioxide, Total
- Calcium
- Protein, Total
- Albumin
- Globulin, Total
- Albumin/Globulin (A/G) Ratio
- Alkaline Phosphatase (ALP)
- AST
- ALT
Prostate health
- Prostate-Specific Antigen (PSA)Male panel
- Free PSAMale panel
- % Free PSAMale panel
Nutrient Status
31 markers
Vitamins & minerals
- Vitamin D, 25-OHD (25-Hydroxy)
- Magnesium, RBC
Iron status
- Iron
- Iron Saturation
- TIBC
- UIBC
- Ferritin
Complete Blood Count (CBC)
- White Blood Count (WBC)
- Red Blood Count (RBC)
- Hemoglobin (Hgb)
- Hematocrit (HCT)
- MCV
- MCH
- MCHC
- Red Cell Distribution Width (RDW)
- Platelets
- Neutrophils
- Neutrophils (Absolute)
- Lymphocytes
- Lymphocytes (Absolute)
- Neutrophil/Lymphocyte Ratio
- Monocytes
- Monocytes (Absolute)
- Eosinophils
- Eosinophils (Absolute)
- Basophils
- Basophils (Absolute)
- Immature Cells
- Immature Granulocytes
- Immature Granulocytes (Absolute)
- NRBC, w/ Reflex for Immature Cells
Clinical evidence
The research behind Vardenafil.
Safety profile
Monitoring & safety information.
Commonly reported side effects
- Headache
- Flushing
- Rhinitis
- Dyspepsia
Less common but serious risks
- QT prolongation (unique among PDE5i, avoid with QT-prolonging drugs)
- Hypotension with nitrates
- Priapism (rare)
Generally not appropriate for
- Concurrent nitrates
- Class IA/III antiarrhythmics
- QT prolongation
Typical monitoring
- Blood pressure
- ECG if cardiac history
- Erectile function assessment
FAQ
Quick answers.
PDE5 inhibitor with the highest PDE5 selectivity and potency among the class. Duration 4 to 5 hours. Often used in combination troches for enhanced sexual function protocols.
Highest PDE5 selectivity. Rapid onset. Potent at lower doses.
Common side effects include: headache, flushing, rhinitis, dyspepsia. Most side effects are dose-dependent and may resolve with continued use or dose adjustment.
PDE5 inhibitor with the highest PDE5 selectivity and potency among the class. Duration 4 to 5 hours. Often used in combination troches for enhanced sexual function protocols.
Treatments are dependent on licensed clinical prescription. Client costs vary based on individual labs and panel in treatments and services.