TesamorelinTesamorelin

Full 44-amino-acid GHRH analog with enhanced stability. Only GHRH analog with current FDA approval (HIV lipodystrophy). Promising cognitive benefit data from The Lancet Healthy Longevity.

HSA/FSA eligible · No commitmentHSA/FSA eligible · No commitment

Peptides · GH Support

Marketing purposes only. Actual medications, if prescribed, are dispensed by a licensed pharmacy.

How it works

From sign-up to treatment.From sign-up to your first dose.

Take the assessment

45-min intake with your dedicated health coach. A free health-score quiz is available before the paid intake.

Get your labs drawn

Complete lab panel ordered by your provider, drawn at any of 4,000 partnered lab locations nationwide. Results typically return within 14 days.

Provider reviews your results

A licensed medical provider reviews your labs and history to evaluate whether Tesamorelin is appropriate for you. Eligibility and any prescription are determined at the provider's discretion.

If eligible, treatment ships to your door

If your provider prescribes Tesamorelin, it ships from a licensed pharmacy. Your coach supports you through follow-up labs and ongoing monitoring.

The baseline panel.

Every Marek client receives this baseline panel before a provider review. Your provider may add additional biomarkers based on your health history, symptoms, and goals, pulling from 1,000+ available markers. See more biomarkers →

Hormone Profile

12 markers

Sex hormones

Total TestosteroneLC/MS
Free TestosteroneEquilibrium Dialysis
Estradiol, Sensitive / UltrasensitiveLC/MS
Sex Hormone Binding Globulin (SHBG)
ProgesteroneLC/MSFemale panel
Prolactin
Luteinizing Hormone (LH)
Follicle-Stimulating Hormone (FSH)
hCG, Total, QuantitativeFemale panel, pre-menopause

Adrenals & neurosteroids

Cortisol
DHEA-S

Growth hormone / IGF-1

Insulin-Like Growth Factor I (IGF-1)

Thyroid Status

3 markers

Thyroid hormones

Thyroid Stimulating Hormone (TSH)
Free T4
Free T3

Heart Health

9 markers

Cardiovascular health

Total Cholesterol
HDL Cholesterol
LDL Cholesterol
LDL:HDL Ratio
VLDL Cholesterol
Triglycerides
Apolipoprotein-B (ApoB)
C-Reactive Protein, High Sensitivity (hsCRP)
Lipoprotein(a) (Lp(a))

Metabolism

3 markers

Insulin sensitivity

Blood Glucose
Fasting Insulin
HbA1c

Organ Function

26 markers

Liver & pancreas

AST
ALT
Bilirubin, Total
γ-Glutamyl Transferase (GGT)

Kidney function

BUN
Creatinine w/ eGFR

Comprehensive Metabolic Panel (CMP)

Glucose
Blood Urea Nitrogen (BUN)
Creatinine
eGFR
BUN/Creatinine Ratio
Sodium
Potassium
Chloride
Carbon Dioxide, Total
Calcium
Protein, Total
Albumin
Globulin, Total
Albumin/Globulin (A/G) Ratio
Alkaline Phosphatase (ALP)
AST
ALT

Prostate health

Prostate-Specific Antigen (PSA)Male panel
Free PSAMale panel
% Free PSAMale panel

Nutrient Status

31 markers

Vitamins & minerals

Vitamin D, 25-OHD (25-Hydroxy)
Magnesium, RBC

Iron status

Iron
Iron Saturation
TIBC
UIBC
Ferritin

Complete Blood Count (CBC)

White Blood Count (WBC)
Red Blood Count (RBC)
Hemoglobin (Hgb)
Hematocrit (HCT)
MCV
MCH
MCHC
Red Cell Distribution Width (RDW)
Platelets
Neutrophils
Neutrophils (Absolute)
Lymphocytes
Lymphocytes (Absolute)
Neutrophil/Lymphocyte Ratio
Monocytes
Monocytes (Absolute)
Eosinophils
Eosinophils (Absolute)
Basophils
Basophils (Absolute)
Immature Cells
Immature Granulocytes
Immature Granulocytes (Absolute)
NRBC, w/ Reflex for Immature Cells

The science

How Tesamorelin works.

Binds pituitary GHRH receptors with high affinity, stimulating pulsatile GH secretion subject to normal somatostatin feedback. Enhanced metabolic stability allows once-daily dosing.

HIV-associated lipodystrophy (FDA-approved)Visceral adiposity / metabolic syndrome (off-label)Cognitive function in MCI (investigational)

Eligibility, dosing, and outcomes vary. Any prescription is at the discretion of a partnered licensed medical provider based on your labs and medical history.

Clinical evidence

The research behind Tesamorelin.

Tesamorelin in HIV-Infected Patients with Abdominal Fat

New England Journal of Medicine (2010)

Phase 3 (n=412): 15.2% VAT reduction vs -0.5% placebo at 26 weeks.

Tesamorelin and Cognition in Older Adults

The Lancet Healthy Longevity (2021)

Improved verbal memory and executive function over 20 weeks in older adults including those with MCI.

Safety profile

Monitoring & safety information.

Commonly reported side effects

Injection site reactions
Peripheral edema
Arthralgias
Nausea
Transient glucose elevation

Less common but serious risks

Fluid retention
Glucose intolerance
Potential malignancy risk (theoretical)

Generally not appropriate for

Active malignancy
Disrupted hypothalamic-pituitary axis
Pregnancy

Typical monitoring

IGF-1
Fasting glucose/HbA1c
Lipid panel
Waist circumference
DXA body composition

FAQ

Quick answers.

Full 44-amino-acid GHRH analog with enhanced stability. Only GHRH analog with current FDA approval (HIV lipodystrophy). Promising cognitive benefit data from The Lancet Healthy Longevity.

Significant VAT reduction (~15 to 18%). FDA-approved with Phase III data. Promising cognitive benefits in aging. Preserved physiologic feedback regulation.

Common side effects include: injection site reactions, peripheral edema, arthralgias, nausea, transient glucose elevation. Most side effects are dose-dependent and may resolve with continued use or dose adjustment.

View all FAQs

See all FAQs

Full 44-amino-acid GHRH analog with enhanced stability. Only GHRH analog with current FDA approval (HIV lipodystrophy). Promising cognitive benefit data from The Lancet Healthy Longevity.

Treatments are dependent on licensed clinical prescription. Client costs vary based on individual labs and panel in treatments and services.