Take the assessment
45-min intake with your dedicated health coach. A free health-score quiz is available before the paid intake.
SermorelinSermorelin
Synthetic GHRH analog (first 29 amino acids of endogenous GHRH). Stimulates pulsatile GH release physiologically, preserving somatostatin feedback. Previously FDA-approved; withdrawn 2008 for manufacturing economics, not safety.
HSA/FSA eligible · No commitmentHSA/FSA eligible · No commitment
Sermorelin
Marketing purposes only. Actual medications, if prescribed, are dispensed by a licensed pharmacy.
How it works
From sign-up to treatment.From sign-up to your first dose.
Get your labs drawn
Complete lab panel ordered by your provider, drawn at any of 4,000 partnered lab locations nationwide. Results typically return within 14 days.
Provider reviews your results
A licensed medical provider reviews your labs and history to evaluate whether Sermorelin is appropriate for you. Eligibility and any prescription are determined at the provider's discretion.
If eligible, treatment ships to your door
If your provider prescribes Sermorelin, it ships from a licensed pharmacy. Your coach supports you through follow-up labs and ongoing monitoring.
The baseline panel.
Every Marek client receives this baseline panel before a provider review. Your provider may add additional biomarkers based on your health history, symptoms, and goals, pulling from 1,000+ available markers. See more biomarkers →
Hormone Profile
12 markers
Sex hormones
- Total TestosteroneLC/MS
- Free TestosteroneEquilibrium Dialysis
- Estradiol, Sensitive / UltrasensitiveLC/MS
- Sex Hormone Binding Globulin (SHBG)
- ProgesteroneLC/MSFemale panel
- Prolactin
- Luteinizing Hormone (LH)
- Follicle-Stimulating Hormone (FSH)
- hCG, Total, QuantitativeFemale panel, pre-menopause
Adrenals & neurosteroids
- Cortisol
- DHEA-S
Growth hormone / IGF-1
- Insulin-Like Growth Factor I (IGF-1)
Thyroid Status
3 markers
Thyroid hormones
- Thyroid Stimulating Hormone (TSH)
- Free T4
- Free T3
Heart Health
9 markers
Cardiovascular health
- Total Cholesterol
- HDL Cholesterol
- LDL Cholesterol
- LDL:HDL Ratio
- VLDL Cholesterol
- Triglycerides
- Apolipoprotein-B (ApoB)
- C-Reactive Protein, High Sensitivity (hsCRP)
- Lipoprotein(a) (Lp(a))
Metabolism
3 markers
Insulin sensitivity
- Blood Glucose
- Fasting Insulin
- HbA1c
Organ Function
26 markers
Liver & pancreas
- AST
- ALT
- Bilirubin, Total
- γ-Glutamyl Transferase (GGT)
Kidney function
- BUN
- Creatinine w/ eGFR
Comprehensive Metabolic Panel (CMP)
- Glucose
- Blood Urea Nitrogen (BUN)
- Creatinine
- eGFR
- BUN/Creatinine Ratio
- Sodium
- Potassium
- Chloride
- Carbon Dioxide, Total
- Calcium
- Protein, Total
- Albumin
- Globulin, Total
- Albumin/Globulin (A/G) Ratio
- Alkaline Phosphatase (ALP)
- AST
- ALT
Prostate health
- Prostate-Specific Antigen (PSA)Male panel
- Free PSAMale panel
- % Free PSAMale panel
Nutrient Status
31 markers
Vitamins & minerals
- Vitamin D, 25-OHD (25-Hydroxy)
- Magnesium, RBC
Iron status
- Iron
- Iron Saturation
- TIBC
- UIBC
- Ferritin
Complete Blood Count (CBC)
- White Blood Count (WBC)
- Red Blood Count (RBC)
- Hemoglobin (Hgb)
- Hematocrit (HCT)
- MCV
- MCH
- MCHC
- Red Cell Distribution Width (RDW)
- Platelets
- Neutrophils
- Neutrophils (Absolute)
- Lymphocytes
- Lymphocytes (Absolute)
- Neutrophil/Lymphocyte Ratio
- Monocytes
- Monocytes (Absolute)
- Eosinophils
- Eosinophils (Absolute)
- Basophils
- Basophils (Absolute)
- Immature Cells
- Immature Granulocytes
- Immature Granulocytes (Absolute)
- NRBC, w/ Reflex for Immature Cells
The science
How Sermorelin works.
Binds GHRH receptors on pituitary somatotrophs, stimulating endogenous GH synthesis and pulsatile release while preserving feedback inhibition from somatostatin and IGF-1.
Age-related GH declineBody composition optimizationSleep quality improvementRecovery enhancement
Eligibility, dosing, and outcomes vary. Any prescription is at the discretion of a partnered licensed medical provider based on your labs and medical history.
Clinical evidence
The research behind Sermorelin.
Sermorelin: A Review of Its Use in Pediatric GHD
BioDrugs (1998)
Improved growth velocity and IGF-1 normalization comparable to rhGH in GH-responsive children with preserved HPG axis regulation.
Safety profile
Monitoring & safety information.
Commonly reported side effects
- Injection site reactions
- Facial flushing
- Headache
- Mild water retention
Less common but serious risks
- Potential stimulation of GH-sensitive malignancies
- Elevated IGF-1 if overdosed
Generally not appropriate for
- Active malignancy
- Hypersensitivity
- Pregnancy
Typical monitoring
- IGF-1 levels
- Fasting glucose/HbA1c
- Thyroid function
- Lipid panel
FAQ
Quick answers.
Synthetic GHRH analog (first 29 amino acids of endogenous GHRH). Stimulates pulsatile GH release physiologically, preserving somatostatin feedback. Previously FDA-approved; withdrawn 2008 for manufacturing economics, not safety.
Physiologic pulsatile GH release. Lower side effect risk vs exogenous GH. Enhances slow-wave sleep. May support immune function.
Common side effects include: injection site reactions, facial flushing, headache, mild water retention. Most side effects are dose-dependent and may resolve with continued use or dose adjustment.
Synthetic GHRH analog (first 29 amino acids of endogenous GHRH). Stimulates pulsatile GH release physiologically, preserving somatostatin feedback. Previously FDA-approved; withdrawn 2008 for manufacturing economics, not safety.
Treatments are dependent on licensed clinical prescription. Client costs vary based on individual labs and panel in treatments and services.