Marek HealthMarek HealthMarek Health
Log inStart treatment online

GlyNAC (Glycine + NAC)

Oral combination (900mg NAC capsule + 2x500mg Glycine capsules)Available in all 50 states

Marketing purposes only. Actual medications, if prescribed, are dispensed by a licensed pharmacy.

longevity

GlyNAC (Glycine + NAC)GlyNAC (Glycine + NAC)

Combination of glycine and N-acetyl cysteine that together provide all three amino acid substrates for glutathione synthesis. Demonstrated reversal of multiple hallmarks of aging in a landmark Baylor College of Medicine study.

Restores glutathione to youthful levels

Reverses multiple hallmarks of aging

Improves mitochondrial function

Reduces oxidative stress and inflammation

No commitment · HSA/FSA eligibleNo commitment · HSA/FSA eligible

How it works

Mechanism of action

NAC provides cysteine (rate-limiting substrate) and glycine provides the second amino acid for glutathione synthesis (glutamate + cysteine + glycine). Combined supplementation restores intracellular glutathione to youthful levels, reversing oxidative stress, mitochondrial dysfunction, inflammation, and insulin resistance.

The baseline panel.

Every Marek client receives this baseline panel before a provider review. Your provider may add additional biomarkers based on your health history, symptoms, and goals, pulling from 1,000+ available markers. See more biomarkers →

Hormone Profile

12 markers

Sex hormones

  • Total TestosteroneLC/MS
  • Free TestosteroneEquilibrium Dialysis
  • Estradiol, Sensitive / UltrasensitiveLC/MS
  • Sex Hormone Binding Globulin (SHBG)
  • ProgesteroneLC/MSFemale panel
  • Prolactin
  • Luteinizing Hormone (LH)
  • Follicle-Stimulating Hormone (FSH)
  • hCG, Total, QuantitativeFemale panel, pre-menopause

Adrenals & neurosteroids

  • Cortisol
  • DHEA-S

Growth hormone / IGF-1

  • Insulin-Like Growth Factor I (IGF-1)

Thyroid Status

3 markers

Thyroid hormones

  • Thyroid Stimulating Hormone (TSH)
  • Free T4
  • Free T3

Heart Health

9 markers

Cardiovascular health

  • Total Cholesterol
  • HDL Cholesterol
  • LDL Cholesterol
  • LDL:HDL Ratio
  • VLDL Cholesterol
  • Triglycerides
  • Apolipoprotein-B (ApoB)
  • C-Reactive Protein, High Sensitivity (hsCRP)
  • Lipoprotein(a) (Lp(a))

Metabolism

3 markers

Insulin sensitivity

  • Blood Glucose
  • Fasting Insulin
  • HbA1c

Organ Function

26 markers

Liver & pancreas

  • AST
  • ALT
  • Bilirubin, Total
  • γ-Glutamyl Transferase (GGT)

Kidney function

  • BUN
  • Creatinine w/ eGFR

Comprehensive Metabolic Panel (CMP)

  • Glucose
  • Blood Urea Nitrogen (BUN)
  • Creatinine
  • eGFR
  • BUN/Creatinine Ratio
  • Sodium
  • Potassium
  • Chloride
  • Carbon Dioxide, Total
  • Calcium
  • Protein, Total
  • Albumin
  • Globulin, Total
  • Albumin/Globulin (A/G) Ratio
  • Alkaline Phosphatase (ALP)
  • AST
  • ALT

Prostate health

  • Prostate-Specific Antigen (PSA)Male panel
  • Free PSAMale panel
  • % Free PSAMale panel

Nutrient Status

31 markers

Vitamins & minerals

  • Vitamin D, 25-OHD (25-Hydroxy)
  • Magnesium, RBC

Iron status

  • Iron
  • Iron Saturation
  • TIBC
  • UIBC
  • Ferritin

Complete Blood Count (CBC)

  • White Blood Count (WBC)
  • Red Blood Count (RBC)
  • Hemoglobin (Hgb)
  • Hematocrit (HCT)
  • MCV
  • MCH
  • MCHC
  • Red Cell Distribution Width (RDW)
  • Platelets
  • Neutrophils
  • Neutrophils (Absolute)
  • Lymphocytes
  • Lymphocytes (Absolute)
  • Neutrophil/Lymphocyte Ratio
  • Monocytes
  • Monocytes (Absolute)
  • Eosinophils
  • Eosinophils (Absolute)
  • Basophils
  • Basophils (Absolute)
  • Immature Cells
  • Immature Granulocytes
  • Immature Granulocytes (Absolute)
  • NRBC, w/ Reflex for Immature Cells

Clinical evidence

The research behind GlyNAC (Glycine + NAC).

Glutathione Decline with Aging and Restoration by GlyNAC

Journal of Nutrition (2021)

Older adults had 50% lower glutathione; GlyNAC for 24 weeks restored glutathione and improved oxidative stress, mitochondrial dysfunction, inflammation, endothelial dysfunction, and insulin resistance.

GlyNAC Improves Multiple Aging Hallmarks

The Journals of Gerontology (2023)

16 weeks of GlyNAC in older adults improved genomic damage, cognition, muscle strength, gait speed, and exercise capacity.

Safety profile

Monitoring & safety information.

Commonly reported side effects

  • GI upset (NAC component)
  • Sulfurous odor (NAC)
  • Nausea

Less common but serious risks

  • None significant at standard doses

Generally not appropriate for

  • Hypersensitivity to NAC
  • Concurrent nitroglycerin IV

Typical monitoring

  • Glutathione levels (whole blood)
  • Oxidative stress markers
  • Fasting glucose/insulin
  • Inflammatory markers

FAQ

Quick answers.

Combination of glycine and N-acetyl cysteine that together provide all three amino acid substrates for glutathione synthesis. Demonstrated reversal of multiple hallmarks of aging in a landmark Baylor College of Medicine study.
Restores glutathione to youthful levels. Reverses multiple hallmarks of aging. Improves mitochondrial function. Reduces oxidative stress and inflammation. Improves insulin sensitivity.
Common side effects include: gi upset (nac component), sulfurous odor (nac), nausea. Most side effects are dose-dependent and may resolve with continued use or dose adjustment.
View all FAQs
See all FAQs

Combination of glycine and N-acetyl cysteine that together provide all three amino acid substrates for glutathione synthesis. Demonstrated reversal of multiple hallmarks of aging in a landmark Baylor College of Medicine study.

Treatments are dependent on licensed clinical prescription. Client costs vary based on individual labs and panel in treatments and services.