Diagnostic Blood Test:
Sex Hormone-Binding Globulin (SHBG)
Sex Hormone-Binding Globulin (SHBG) is a protein made in the liver that binds to sex hormones, helping to stabilize and transport them to the body’s tissues. Abnormal SHBG levels can lead to hormonal imbalances, metabolic dysfunction, and decreased sexual function. Low SHBG may also be a sign of thyroid conditions, diabetes, polycystic ovary syndrome (PCOS), or cancer, while high levels can signal problems with the liver, thyroid, pituitary gland, or testicles.
Note: This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin. Cease biotin supplementation at least 72 hours prior to blood draw.