Written by Hayim Pinson
Last updated: 9/26/2022

IGF-1, or Insulin-Like Growth Factor, is a hormone naturally secreted in the body and a significant mediator of the beneficial effects of Human Growth Hormone. In children, these hormones are critical for bone and other tissue development. Still, as we age, the pharmacokinetics change slightly, and we can capitalize on these changes to achieve better living through science.

What is IGF-1?

IGF-1 is a natural peptide consisting of 70 Amino Acids and is stimulated primarily by Human Growth Hormone. As we age, we have less active HGH and IGF-1 within the body, which can cause a few adverse effects: [2]

  • Decreased bone density
  • Poor hair and skin health
  • Reduced cardiovascular fitness
  • Poor recovery from training
  • Depression
  • Difficulty losing stubborn fat

After the age of 30, our levels of HGH decrease by 1-2% year over year.

All in all, having lower levels of IGF-1 is not a fun time. But fear not, replacement to levels of a young, healthy adult is possible.

Replenishing IGF-1 Levels

Doctors are well-versed in treating Growth Hormone/IGF-1 deficiency. They often use these therapies to treat dwarfism. Unfortunately, HGH is pricey; however, the team at Marek Health uses cutting-edge treatments to help you achieve optimal HGH/IGF-1 levels without breaking the bank.

  • GHRP & GHRH Peptides: Growth Hormone production can be stimulated optimally with a combination of a GHRP (Growth Hormone Releasing Peptide) and GHRH (Growth Hormone Releasing Hormone). Studies show that using these two together results in higher levels of Growth Hormone. [2] The team at Marek Health are fans of newer generation peptides such as Tesamorelin, Ipamorelin, and CJC 1925, which seem to be safer and more effective than previous generations of peptides.
  • MK 677: MK 677 or ibutamoren is known as a Ghrelin Mimetic that can increase basal production of HGH in the body, leading to increased IGF-1 levels. The main benefit of MK 677 is that it is administered orally. [3]

Pros of HGH/IGF-1 Treatment

  • HGH is directly linked to reduced adipose tissue levels and seems very effective against visceral fat deposits. [4]
  • HGH treatment lowers LDL cholesterol (the bad kind of cholesterol). [4]
  • HGH treatment has been shown to positively affect bone density [5] and can reduce the risk of fractures. [6]
  • In vivo studies show that in untrained adults, you can have some muscle growth from IGF-1 treatment. Not going to make you Arnold, but it will surely help your grandma grow a bit (she needs it). [7]
  • IGF-1 has also been linked to better hair growth and health. [8]

Cons of HGH/IGF-1 Treatment

Are there any cons to HGH/IGF-1 treatment? Well, sure. Any treatment can have cons, and these two are no different:

  • Due to increased levels of Glucagon, elevated HGH/IGF-1 can lead to insulin resistance if abused. However, this takes a long time to happen and is easily managed. The medical team at Marek Health can help you implement strategies to optimize insulin sensitivity.
  • High levels of HGH/IGF-1 can also lead to water retention, so if you suffer from high blood pressure, you must be careful with the stuff. Again, easily managed if you work with medical professionals.

HGH and IGF-1 treatments are pretty simple, effective, and cost-efficient if you look at their benefits. HGH has been called the ”hormone of youth” for a good reason. It’s extremely powerful and great at making you feel better.


HGH treatment was initially developed to treat kids and young people suffering from dwarfism. There is no shame in having lower levels of HGH; it happens to most of us as we age. As the years went by, scientists and researchers soon realized how effective treating low levels of HGH/IGF-1 would be for many individuals.

Marek Health is excellent at helping clients improve their lives in many ways, from better hair, skin, muscle tone, fat loss, and much more. The best part is that it’s completely legal and reasonably priced. You also work hand in hand with medical staff, so the chances of adverse effects are pretty low.

HGH/IGF-1 treatment has changed the lives of patients time and time again. Better health over
an extended period will significantly improve your quality of life.

This article was written by Hayim Pinson, Muscle and Brawn’s Editor and Chief. Check out their website for more resources, training, ebooks, clinics, product reviews, and more to help you along your health optimization journey.
You can also follow them on Instagram @muscleandbrawn.

This blog post/article is for informational purposes only and does not constitute medical advice. This is not a substitute for professional medical advice and should not be relied upon. If you are considering a treatment, always consult your primary care physician to discuss the risks and benefits.